On Wednesday 10th July, Prof. Sydney Brenner, 2002 Nobel laureate in Physiology or Medicine, paid a rapid visit to the IBE taking advantage of his 48h-stay in Barcelona to attend 8 ^th European Zebrafish Meeting. We give him the IBE Annual Report corresponding to 2012, and commented together the IBE Research Programs and general activities. Prof. Brenner promised to come back next year for a longer and quieter visit.